USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: GBB4_HUMAN USC-OGP 2-DE database:  GBB4_HUMAN GBB4_HUMAN General information about the entry View entry in simple text format Entry name GBB4_HUMAN Primary accession number Q9HAV0 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Guanine nucleotide-binding protein subunit beta-4; AltName: Full=Transducin beta chain 4;. Gene name Name=GNB4 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0464: pI=5.21; Mw=33566 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0746: pI=5.21; Mw=34473 Cross-references UniProtKB/Swiss-Prot Q9HAV0; GBB4_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name GBB4_HUMAN Primary accession number Q9HAV0 Secondary accession number(s) B3KMH5 D3DNR8 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 151) Name and origin of the protein Description RecName: Full=Guanine nucleotide-binding protein subunit beta-4; AltName: Full=Transducin beta chain 4; Gene name Name=GNB4 Encoded on Name=GNB4 Keywords Acetylation; Charcot-Marie-Tooth disease; Complete proteome; Direct protein sequencing; Disease mutation; Neurodegeneration; Neuropathy; Phosphoprotein; Reference proteome; Repeat; Transducer; WD repeat. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF300648; AAG18442.1; -; mRNA EMBL AK001890; BAG50987.1; -; mRNA EMBL CH471052; EAW78403.1; -; Genomic_DNA EMBL CH471052; EAW78404.1; -; Genomic_DNA EMBL BC000873; AAH00873.1; -; mRNA CCDS CCDS3230.1; -; . RefSeq NP_067642.1; NM_021629.3; . RefSeq XP_005247749.1; XM_005247692.2; . RefSeq XP_006713784.1; XM_006713721.2; . UniGene Hs.173030; -; . ProteinModelPortal Q9HAV0; -; . SMR Q9HAV0; -; . BioGrid 121887; 67; . IntAct Q9HAV0; 18; . MINT MINT-1135986; -; . STRING 9606.ENSP00000232564; -; . iPTMnet Q9HAV0; -; . PhosphoSitePlus Q9HAV0; -; . SwissPalm Q9HAV0; -; . BioMuta GNB4; -; . DMDM 22256759; -; . OGP Q9HAV0; -; . EPD Q9HAV0; -; . MaxQB Q9HAV0; -; . PaxDb Q9HAV0; -; . PeptideAtlas Q9HAV0; -; . PRIDE Q9HAV0; -; . DNASU 59345; -; . Ensembl ENST00000232564; ENSP00000232564; ENSG00000114450; . Ensembl ENST00000468623; ENSP00000419693; ENSG00000114450; . GeneID 59345; -; . KEGG hsa:59345; -; . UCSC uc003fjv.5; human; . CTD 59345; -; . DisGeNET 59345; -; . GeneCards GNB4; -; . HGNC HGNC:20731; GNB4; . HPA CAB018383; -; . HPA CAB018737; -; . HPA HPA040736; -; . MalaCards GNB4; -; . MIM 610863; gene; . MIM 615185; phenotype; . neXtProt NX_Q9HAV0; -; . OpenTargets ENSG00000114450; -; . Orphanet 352670; Autosomal dominant intermediate Charcot-Marie-Tooth disease type F; . PharmGKB PA134864200; -; . eggNOG KOG0286; Eukaryota; . eggNOG ENOG410XQUX; LUCA; . GeneTree ENSGT00760000119239; -; . HOGENOM HOG000176356; -; . HOVERGEN HBG000188; -; . InParanoid Q9HAV0; -; . KO K04538; -; . OMA DYKTFVS; -; . OrthoDB EOG091G0A7T; -; . PhylomeDB Q9HAV0; -; . TreeFam TF106149; -; . Reactome R-HSA-163359; Glucagon signaling in metabolic regulation; . Reactome R-HSA-202040; G-protein activation; . Reactome R-HSA-381676; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; . Reactome R-HSA-392170; ADP signalling through P2Y purinoceptor 12; . Reactome R-HSA-392451; G beta:gamma signalling through PI3Kgamma; . Reactome R-HSA-392851; Prostacyclin signalling through prostacyclin receptor; . Reactome R-HSA-400042; Adrenaline; noradrenaline inhibits insulin secretion; . Reactome R-HSA-4086398; Ca2+ pathway; . Reactome R-HSA-416476; G alpha (q) signalling events; . Reactome R-HSA-416482; G alpha (12/13) signalling events; . Reactome R-HSA-418217; G beta:gamma signalling through PLC beta; . Reactome R-HSA-418555; G alpha (s) signalling events; . Reactome R-HSA-418592; ADP signalling through P2Y purinoceptor 1; . Reactome R-HSA-418594; G alpha (i) signalling events; . Reactome R-HSA-418597; G alpha (z) signalling events; . Reactome R-HSA-420092; Glucagon-type ligand receptors; . Reactome R-HSA-428930; Thromboxane signalling through TP receptor; . Reactome R-HSA-432040; Vasopressin regulates renal water homeostasis via Aquaporins; . Reactome R-HSA-456926; Thrombin signalling through proteinase activated receptors (PARs); . Reactome R-HSA-500657; Presynaptic function of Kainate receptors; . Reactome R-HSA-6814122; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; . SignaLink Q9HAV0; -; . ChiTaRS GNB4; human; . GeneWiki GNB4; -; . GenomeRNAi 59345; -; . PRO PR:Q9HAV0; -; . Proteomes UP000005640; Chromosome 3; . Bgee ENSG00000114450; -; . CleanEx HS_GNB4; -; . ExpressionAtlas Q9HAV0; baseline and differential; . Genevisible Q9HAV0; HS; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005765; C:lysosomal membrane; IDA:UniProtKB; . GO GO:0043209; C:myelin sheath; IEA:Ensembl; . GO GO:0005886; C:plasma membrane; TAS:Reactome; . GO GO:0032403; F:protein complex binding; IDA:MGI; . GO GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW; . GO GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome; . GO GO:0006457; P:protein folding; TAS:Reactome; . GO GO:0021762; P:substantia nigra development; IEP:UniProtKB; . Gene3D 2.130.10.10; -; 1; . InterPro IPR020472; G-protein_beta_WD-40_rep; . InterPro IPR001632; Gprotein_B; . InterPro IPR016346; Guanine_nucleotide-bd_bsu; . InterPro IPR015943; WD40/YVTN_repeat-like_dom; . InterPro IPR001680; WD40_repeat; . InterPro IPR019775; WD40_repeat_CS; . InterPro IPR017986; WD40_repeat_dom; . PANTHER PTHR19850; PTHR19850; 1; . Pfam PF00400; WD40; 7; . PRINTS PR00319; GPROTEINB; . PRINTS PR00320; GPROTEINBRPT; . SMART SM00320; WD40; 7; . SUPFAM SSF50978; SSF50978; 1; . PROSITE PS00678; WD_REPEATS_1; 3; . PROSITE PS50082; WD_REPEATS_2; 6; . PROSITE PS50294; WD_REPEATS_REGION; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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